李明 副教授，硕士生导师
Email：leeming@ynu.edu.cn
个人简介：
李明，博士，云南大学副教授。
2003年毕业于中国农业大学，获理学博士学位，次年在云南大学生命科学学院从事教学和科研工作。
早期主要从事胚胎干细胞方面的研究，近年来以寄生蜂-斜纹夜蛾作为模式系统，开展了昆虫先天免疫方面的研究，主要探讨了亲免素蛋白家族在茧蜂寄生斜纹夜蛾过程中发挥免疫抑制作用的分子机理，为农林害虫的生物防治提供了一些理论基础。期间主持了“亲环素A在斜纹夜蛾细胞免疫抑制反应中作用机理的研究“、”茧蜂病毒调控亲免素D通过线粒体途径诱导寄主血细胞凋亡的研究”和““茧蜂病毒通过亲免素J负调控NF-κB信号通路抑制寄主免疫反应的研究”等三项国家自然科学基金项目和2项省基金，以第一作者和通讯作者共发表科研论文约30余篇，编写教材1本，获云南省科技二等奖1项,专利申请2项。
招生专业：
细胞生物学硕士
研究方向：近年以寄生蜂-斜纹夜蛾为模式系统，主要开展昆虫先天免疫方面的研究。
代表性研究成果：
1. Dan Yu, Pan Zhang, Cuixian Xu, Yan Hu, Yaping Liang, Ming Li*..Microplitis bicoloratus Bracovirus Promotes Cyclophilin D-Acetylation at Lysine 125 That Correlates with Apoptosis during Insect Immunosuppression. Viruses. 2023, 15: 1491.
2. Pan Zhang, Zi-Yan Liu, Dan Yu, Cui-Xian Xu, Yan Hu, Ya-Ping Liang, Jie Jin, Ming Li*. Microplitis bicoloratus parasitism promotes cyclophilin D-p53 interaction to induce apoptosis of hemocytes in Spodoptera litura. Arch Insect Biochem Physiol. 2022, e21970.
3. Yan Hu, Ya-Ping Liang, Hang-Yu Tian, Cui-Xian Xu, Dan Yu, Hui Ye, Ming Li*，Microplitis bicoloratus bracovirus regulates cyclophilin A-apoptosis-inducing factor interaction to induce cell apoptosis in the insect immunosuppressive process. Arch Insect Biochem Physiol. 2022, e21877.
4. Shirui Tan#, Fang Yan#, Qingrong Li#, Yaping Liang, Junxu Yu, Zhenjun Li, Feifei He*, Rongpeng Li* and Ming Li*. Chlorogenic Acid Promotes Autophagy and Alleviates Salmonella Typhimurium Infection Through the lncRNAGAS5/miR-23a/PTEN Axis and the p38 MAPK Pathway. Frontiers in Cell and Developmental Biology, 2020, 8 (552020).
5. Hangyu Tian#, Yan Hu#, Pan Zhang#, Wenxi Xing, Cuixian Xu, Dan Yu, Yang Y, Kaijun Luo*, Ming Li*, Spodoptera litura cyclophilin A is required for Microplitis bicoloratus bracovirus-induced apoptosis during insect cellular immune response. Arch Insect Biochem Physiol. 2019, 100(3): 1-15
6. Hangyu Tian#, Dan Yu#, Yan Hu, Pan Zhang, Yang Yang, Qiang Hu* and Ming Li*, Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes, MOLECULAR MEDICINE REPORTS 18: 4349-4355, 2018
7. Ming Li#, Zunyu Pang#, Wei Xiao#, Xinyi Liu#, Yan Zhang, Dongshuai Yu, Minjun Yang，Yang Yang, Jiansheng Hu, Kaijun Luo*. A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratus. PLOS ONE, 2014, 9(10): e110967.
8. Ming Li, Yong-Hai Li, Yi Hou, Xiao-Fang Sun, Qingyuan Sun and Wei-Hua Wang*. Isolation and culture of pluripotent cells from in vitro produced porcine embryos. Zygote, 2004, 12: 43-48.
9. Ming Li, Wei Ma, Yi Hou, Xiao-Fang Sun, Qing-Yuan Sun and Wei-Hua Wang*. Improved isolation and culture of embryonic stem cells from Chinese miniature pig. Journal of Reproduction and Development, 2004, 50(2): 237-244.
10. Ming Li, Dong Zhang, Li-Hong Jiao, Xing Zheng and Wei-Hua Wang*. Isolation and culture of embryonic stem cells from porcine blastocysts. Molecular Reproductive and Development, 2003, 65: 429-434.
