沈俊岭 副教授，硕士生导师
Email：jlshen@ynu.edu.cn
个人简介：
沈俊岭，博士、副教授、硕士生导师。以通讯/第一身份在Science China Life Sciences、FEBS Journal、 Cancer Biology and Medicine等国际一流学术期刊发表10余篇。主持国家自然基金地区项目、云南省重点项目等。
招生专业：
生物化学与分子生物学硕士
细胞生物学硕士
生物与医药——01细胞生物学、生物化学与分子生物学方向
研究方向：
近年以肿瘤细胞和小鼠为模式系统，重点开展以下研究：
1． 钙池操纵的钙内流（SOCE）介导线粒体功能调控癌症发生恶化及肿瘤抗药性的分子机制
2． 肿瘤发生与转移机制研究
代表性研究成果：
1. Qinggang Hao†, Yan Bai†, Ruiqi Guan, Rui Dong, Weiyu Bai, Hayam Hamdy , Liqiong Wang, Mingyao Meng, Yan Sun*, Junling Shen* & Jianwei Sun* . VPS35/retromer dependent MT1-MMP regulation confer melanoma metastasis. Science China Life Sciences. 2025，68（7）：1996-2009. .doi: 10.1007/s11427-024-2884-2.
2. Rui Dong#, Jing Wang#, Ruiqi Guan, Jianwei Sun, Ping Jin*, Junling Shen*. Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer.Antioxidants 2025, 14(1), 104; https://doi.org/10.3390/antiox14010104
3. Weiyu Bai#, Chenghao Yan#, Yichen Yang#, Lei Sang, Qinggang Hao, Xinyi Yao,Yingru Zhang，Jia Yu， Yifan Wang，Xiaowen Li，Mingyao Meng， Jilong Yang, Junling Shen*, Yan Sun*, Jianwei Sun*. EGF/EGFR-YAP1/TEAD2 signaling upregulates STIM1 in vemurafenib resistant melanoma cells. FEBS Journal. 2024 Nov;291(22):4969-4983. doi: 10.1111/febs.17272.
4. Qinggang Hao#, Rui Dong#, Weiyu Bai#, Dong Chang#, Xinyi Yao, Yingru Zhang, Huangying Xu, Huiyan Li, Xiang Kui, Feng Wang*, Yan Wang*, Chengqin Wang*, Yujie Lei*, Yan Chen*, Junling Shen*, Lei Sang*, Yan Bai*, Jianwei Sun*. Screening for metastasis-related genes in mouse melanoma cells through sequential tail vein injection. Biophysics Reports. 2024 Feb 29;10(1):15-21.doi: 10.52601/bpr.2023.230043.
5. 董瑞#，关瑞琪#，高亚可#，郎啟春，沈俊岭*，孙建伟*. 线粒体参与调控卵母细胞发育潜能的研究进展. 中国细胞生物学报， 2024 年1月， 46（1）：90-99. doi:10.11844/cjcb.2024.01.0008.
6. Ksenia Golub#, Weiyu Bai#, Zhimeng Zhang#, Huilin Xiao, Rongyuan Sun, Junling Shen*, Jianwei Sun*. The mechanism and consequences of BRAF inhibitor resistance in melanoma. Genome instability & disease (2023). https://doi.org/10.1007/s42764-023-00105-5
7. Weiyu Bai#, Qinggang Hao#, Zhimeng Zhang#, Bingxing Han, Huilin Xiao, Dong Chang, Yun Zhu*, Junling Shen*, Jianwei Sun*. Identification of a novel inflammation-related gene signature for predicting inflammatory breast cancer survival. Genome instability & disease 2023, 4, 154–175 (2023). doi: https://doi.org/10.1007/s42764-023-00102-8
8. Junling Shen#, Jilong Yang#, Lei Sang, Rui Sun, Weiyu Bai, Chao Wang, Yan Sun*, Jianwei Sun*. PYK2 mediates the BRAF inhibitor (vermurafenib)-induced invadopodia formation and metastasis in melanomas. Cancer Biology and Medicine. 2021 Sep 28;19(8):1211-1223. doi: 10.20892/j.issn.2095-3941.2020.0294
