职晓阳 博士，硕士生导师
Email：xyzhi@ynu.edu.cn
个人简介：
职晓阳，博士，副研究员。云南省“万人计划”青年拔尖人才。
原核微生物系统学与进化生物学。借助生物信息学技术，开展涉及微生物代谢通路的分子进化、原核微生物特定类群的系统发育基因组学、特殊生境微生物生态适应的组学机制、以及病原菌群体基因组学等方向的研究工作。在Nat Commun、JBC、MPE、GBE等国际刊物发表SCI论文50余篇，教材1部。先后获云南省科学技术奖（自然科学类一等、二等）、教育部自然科学奖（二等）。
招生专业：
微生物学硕士
生物信息学硕士
生物与医药——微生物学方向
研究方向：
近年原核生物为对象，重点开展以下研究：
1、原核生物系统分类学
2、病原菌的种下分化与群体基因组学
3、系统发育基因组学中的泛基因组分析算法开发
4、病原菌群体基因组的数据库开发
代表性研究成果：
1. Tang SK†, Zhi XY†, Zhang Y†, Makarova K-S†, Liu BB†, Zheng GS, ..., Koonin EV*, Zhao GP*, Xu P*. Cellular differentiation into hyphae and spores in halophilic archaea. Nat Commun. 2023 14:1827.
2. Wang M†, Li CJ†, Zhang Z, Li PP, Yang LL, Zhi XY*. The evolution of morphological development is congruent with the species phylogeny in the genus Streptomyces. Front Microbiol. 2023 14:1102250.
3. Tan W†, Liao TH†, Wang J, Ye Y, Wei YC, Zhou HK, Xiao Y, Zhi XY*, Zhao ZH*, Lyu LD*, Zhao GP*. A recently evolved diflavin-containing monomeric nitrate reductase is responsible for highly efficient bacterial nitrate assimilation. J Biol Chem. 2020 295(15):5051-5066.
4. Zhi XY*, Jiang Z, Yang LL, Huang Y. The underlying mechanisms of genetic innovation and speciation in the family Corynebacteriaceae: A phylogenomics approach. Mol Phylogenet Evol. 2017 107:246-255.
5. Zhi XY†*, Yao JC†, Li HW, Huang Y, Li WJ*. Genome-wide identification, domain architectures and phylogenetic analysis provide new insights into the early evolution of shikimate pathway in prokaryotes. Mol Phylogenet Evol. 2014 75:154-64.
6. Yin YR†, Meng ZH†, Hu QW, Jiang Z, Xian WD, Li LH, Hu W, Zhang F, Zhou EM, Zhi XY*, Li WJ*. The Hybrid Strategy of Thermoactinospora rubra YIM 77501T for Utilizing Cellulose as a Carbon Source at Different Temperatures. Front Microbiol. 2017 8:942.
7. Yang LL, Tang SK, Huang Y, Zhi XY*. Low Temperature Adaptation Is Not the Opposite Process of High Temperature Adaptation in Terms of Changes in Amino Acid Composition. Genome Biol Evol. 2015, 7(12): 3426-3433.
8. Zhi XY†*, Yao JC, Li HW, Huang Y, Li WJ*. Genome-wide identification, domain architectures and phylogenetic analysis provide new insights into the early evolution of shikimate pathway in prokaryotes. Mol Phylogenet Evol. 2014, 75:154-164.
9. Zhi XY†*, Yao JC, Tang SK, Huang Y, Li HW, Li WJ*. The futalosine pathway played an important role in menaquinone biosynthesis during early prokaryote evolution. Genome Biol Evol. 2014, 6: 149-160.
10. Zhi XY, Tang SK, Li WJ. Genus I. Jiangella Song, Li, Wang, Chen, Zhang and Xu 2005. In Bergey's Manual of Determinative Bacteriology Volume 5, The Actinobacteria, Whitman W.B., Goodfellow M., Kämpfer P., et al., Eds. 2012 Springer Press.
