李华 助理研究员，硕士生导师
云南省兴滇英才计划青年人才
Email：hualee@ynu.edu.cn
个人简介：
李华，2011年本科毕业于中国科学技术大学，2017年博士毕业于中国科学院遗传与发育生物学研究所。2018年-2020年于美国北卡罗来纳州中央大学药学系进行博士后研究。2021年至今任云南大学生命科学学院助理研究员。现主要聚焦于皮肤等纤维化疾病，通过遗传学与功能实验鉴定驱动纤维化的核心基因并解析其上下游信号网络。主持云南省自然科学基金青年和面上等项目。
招生专业：
细胞生物学硕士
代表性研究成果：
1. Zhou K#, Wu G#, Dong R, Kan C, Xie L, Gao L, Li H*, Sun J*, & Ning W*. (2025). Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying. Cell regeneration (London, England), 14(1), 25. doi.org/10.1186/s13619-025-00242-0.
2. Li H#, He Y#, Wang Y#, Xie L, Wu G, Liu X, Duan X, Zhou, K, & Ning W*. (2024). The RhoGAP ARHGAP32 interacts with desmoplakin, and is required for desmosomal organization and assembly. Journal of cell science, 137(18), jcs261901. doi.org/10.1242/jcs.261901.
3. Xie L#, Wu G, Liu X, Duan X, Zhou K, Li H*, & Ning W*. (2024). The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions. European journal of cell biology, 103(2), 151426. doi.org/10.1016/j.ejcb.2024.151426.
4. Wang Y#, Teng Z#, Li H#, Wang W, Xu F, Sun K, Chu J, Qian Y, Loake GJ, Chu C, Tang J. (2023) An activated form of NB-ARC protein RLS1 functions with cysteine-rich receptor-like protein RMC to trigger cell death in rice. Plant Communications. Mar 13;4(2):100459. doi: 10.1016/j.xplc.2022.100459. Epub 2022 Oct 6. PMID: 36203361; PMCID: PMC10030324.
5. Ning W#, Muroyama A, Li H, & Lechler T*. (2021). Differentiated Daughter Cells Regulate Stem Cell Proliferation and Fate through Intra-tissue Tension. Cell stem cell, 28(3), 436–452.e5. doi.org/10.1016/j.stem.2020.11.002.
6. Li H, Kittur FS, Hung CY, Li PA, Ge X, Sane DC, Xie J*. (2020). Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model. Frontier in Cellular Neuroscience. Sep 1;14:272. doi: 10.3389/fncel.2020.00272. PMID: 33033473; PMCID: PMC7491318.
7. Li H, Hu B, Chu C*. (2017) Nitrogen use efficiency in crops: lessons from Arabidopsis and rice. Journal of Experimental Botony. May 1;68(10):2477-2488. doi: 10.1093/jxb/erx101. PMID: 28419301.
8. Li H, Hu B, Wang W, Zhang Z, Liang Y, Gao X, Li P, Liu Y, Zhang L, Chu C*. (2016) Identification of microRNAs in rice root in response to nitrate and ammonium. Journal of Genetics and Genomics. Nov 20;43(11):651-661. doi: 10.1016/j.jgg.2015.12.002. Epub 2016 May 24. PMID: 27372185.
9. Hu B, Wang W, Ou S, Tang J, Li H, Che R, Zhang Z, Chai X, Wang H, Wang Y, Liang C, Liu L, Piao Z, Deng Q, Deng K, Xu C, Liang Y, Zhang L, Li L, Chu C*. (2015) Variation in NRT1.1B contributes to nitrate-use divergence between rice subspecies. Nature Genetics. Jul;47(7):834-8. doi: 10.1038/ng.3337. Epub 2015 Jun 8. PMID: 26053497.
